Characterization of αPD-1, αCTLA-4, and αLAG-3 as mono and combination therapy in live tumor fragments using an ex vivo cytokine profiling platform 

This poster characterizes cytokine responses to single agent and combination immune checkpoint inhibitors beyond PD-1 in live tumor fragments generated from resections and core needle biopsies, revealing that unique cytokine signatures are observed for individual tumor specimens, regardless of treatment condition. In the video below, Erika von Euw, PhD, MBA walks you through the poster presented at AACR IO 2026.